H. Lundbeck A/S strengthens its pipeline of pharmaceuticals in clinical development by initiating phase IIa clinical studies with the innovative project Lu AA24493 in order to evaluate safety and tolerability and to explore theoretical efficacy parameters of the drug in humans. Lundbeck expects to enrol 35-40 people suffering from Friedreich's ataxia in this study.
Novartis announced that it received approval from the German regulatory authorities for its adjuvanted cell culture-based Influenza A(H1N1) 2009 monovalent vaccine, Celtura®. Novartis continues to pursue registration in other major countries, including Japan and Switzerland.
There are increasingly more research groups that try to discover the mechanisms of cell differentiation in order to reprogramme differentiated cells. On this occasion, investigators from the CRG have described a process of cell reprogramming which results in morphologically and functionally distinct cells with a 100% efficiency rate.
Are you a female athlete or just someone who likes challenging workouts -- who also wants to get pregnant? It may make sense to ease off a bit as you try to get pregnant. New research from the Norwegian University of Science and Technology (NTNU) shows that the body may not have enough energy to support both hard workouts and getting pregnant.
Middle-aged women with high levels of a specific amino acid in their blood are twice as likely to suffer from Alzheimer's many years later, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden. This discovery this could lead to a new and simple way of determining who is at risk long before there are any signs of the illness.
Drugs sometimes have beneficial side effects. A glaucoma treatment causes luscious eyelashes. A blood pressure drug also aids those with a rare genetic disease. The newest surprise discovered by researchers at the Johns Hopkins University School of Medicine is a gonorrhea medication that might help battle cancer.
A compound already used to treat pneumonia could become a new therapy for an inherited muscular wasting disease, according to researchers at the University of Oregon and the University of Rochester School of Medicine and Dentistry in New York.
Researchers at Wake Forest University School of Medicine and the University of Wisconsin-Madison have discovered that some elevated prostate-specific antigen (PSA) levels in men may be caused by a hormone normally occurring in the body, and are not necessarily a predictor of the need for a prostate biopsy.
A rapid decline in metabolic activity on a PET scan after radiation therapy for non-small cell lung cancer is correlated with good local tumor control, according to a study presented by researchers at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting.
A small group of patients with severe Graves' eye disease experienced rapid improvement of their symptoms and improved vision following treatment with the drug rituximab. Inflammation around their eyes and damage to the optic nerve were significantly reduced. The same patients had not previously responded to steroids, a common treatment for Graves' eye disease. Raymond S. Douglas, M.D., Ph.
Oncolytics Biotech Inc. (TSX:ONC, NASDAQ:ONCY) ("Oncolytics" or the "Company") announced updated results from a Phase II study of intravenous REOLYSIN(R) in patients with sarcomas metastatic to the lung in a poster presentation at the 15th Annual Connective Tissue Oncology Society Meeting held in Miami Beach, Florida, from November 5th to 7th.
Novexel, a speciality pharmaceutical company focused on the discovery and development of novel antibiotics designed to overcome the significant global problem of microbial resistance, announces that its most advanced oral antibacterial NXL103 (flopristin/linopristin), has started a Phase II clinical trial in adults with acute bacterial skin and skin structure infections (ABSSSI).
CEL-SCI Corporation (NYSE Amex: CVM), a developer of vaccines and therapeutics for the prevention and treatment of infectious diseases and a late-stage oncology company, announced today that an Institutional Review Board of The Johns Hopkins University School of Medicine (Johns Hopkins) has given clearance for the Company's first clinical study to proceed.
Rhode Island Hospital has received an $11 million grant to fund research that will lead to a general understanding of stem cell biology and identify unique approaches to tissue regeneration in lung and marrow diseases.
Scientists at Michigan State University are receiving nearly $3 million from the National Institutes of Health to uncover how several popular plants make medicinal compounds.
The National Institutes of Health (NIH) has awarded researchers in Rice University's new BioScience Research Collaborative (BRC) a $2 million Grand Opportunity (GO) grant to develop a fast, inexpensive test for oral cancer that a dentist could perform simply by using a brush to collect a small sample of cells from a patient's mouth.
UCSF HIV researchers have received two NIH grants of $1 million each to study the use of web-based, patient controlled personal health records to improve health and HIV prevention outcomes for HIV positive patients. Both studies are funded through the federal stimulus bill, The American Recovery and Reinvestment Act.
A new study by a team of researchers led by Crislyn D'Souza-Schorey, associate professor of biological sciences at the University of Notre Dame, sheds light on the molecular basis by which tumor cells modulate their surroundings to favor cancer progression.
A dental abscess, or tooth abscess, is an accumulation of pus that forms inside the teeth or gums. The abscess typically originates from a bacterial infection, often one that has accumulated in the soft pulp of the tooth. Bacteria exist in plaque, a by-product of food, saliva and bacteria in the mouth which sticks to the teeth and damages them, as well as the gums.
Prevalence of lactose intolerance may be far lower than previously estimated, according to a study in the latest issue of Nutrition Today. The study, which uses data from a national sample of three ethnic groups, reveals that the overall prevalence rate of self-reported lactose intolerance is 12 percent - with 7.72 percent of European Americans, 10.05 percent of Hispanic Americans and 19.
Embryonic development is like a well-organised building project, with the embryo's DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.
A unique large-scale research device from Jülich has gone into operation in the USA. At the strongest neutron source in the world, the spallation source SNS in Oak Ridge, Tennessee, Forschungszentrum Jülich inaugurated a so-called neutron spin echo (NSE) spectrometer. The NSE spectrometer enables detailed observations to be made of the motion of proteins and polymers.
Many parents like to meddle in their children's lives. Sometimes this can be beneficial, if the meddling is in the form of parental guidance or setting rules. However, numerous studies have found that in Western countries, when parents are very controlling and dominating over their children, the children suffer psychologically.
The Journal of Infectious Diseases has released a special edition, Global Rotavirus Surveillance: Preparing for the Introduction of Rotavirus Vaccines. This special edition provides a significant contribution to the understanding of rotavirus disease burden and the impact of rotavirus vaccines, which have the potential to save an estimated 228,000 lives annually.
For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options.
The Stop ALD Foundation has applauded the investigators who are reporting in the current issue of Science successful results from the pioneering use of gene therapy for adrenoleukodystrophy (ALD), a potentially crippling and fatal brain disorder in young boys.
Complete Genomics, a third-generation human genome sequencing company, has announced publication of a report in the journal Science describing its proprietary DNA sequencing platform, including analysis of sequence data from three complete human genomes.
A gene associated with longevity in roundworms and humans has been shown to affect the function of stem cells that generate new neurons in the adult brain, according to researchers at the Stanford University School of Medicine. The study in mice suggests that the gene may play an important role in maintaining cognitive function during aging.
When it comes to plants' innate immunity, like many of the dances of life, it takes two to tango. A receptor molecule in the plant pairs up with a specific molecule on the invading bacteria and, presto, the immune system swings into action to defend against the invasion of the disease-causing microbe.
A University of Colorado at Boulder team has developed the first atlas of bacterial diversity across the human body, charting wide variations in microbe populations that live in different regions of the human body and which aid us in physiological functions that contribute to our health.
Declining kidney function is linked to a higher risk of heart failure, heart attack, peripheral arterial disease, and early death in individuals with or without kidney disease, according to a pair of studies appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).
The whole genome sequence of the domestic horse has been completed by the genome-sequencing center of The Broad Institute of MIT and Harvard, in collaboration with an international team of researchers that includes scientists at the University of California, Davis.
Antibiotic over-prescription is promoted by pediatricians' perception of parents' expectations. Research published in the open access journal BMC Pediatrics shows that pediatricians are more likely to inappropriately prescribe antibiotics for respiratory tract infections if they perceived parents were expecting a prescription.
Researchers reporting in BioMed Central's open access journal Conflict and Health found that the discrepancy in media reporting of casualty numbers in the Iraq conflict can potentially misinform the public and contribute to distorted perceptions and gross underestimates of the number of civilians killed in the armed conflict.
Community-based education and awareness programs minimized the death toll from the recent Samoan tsunami, though there are still ways to improve the warning and evacuation process, according to a team of researchers that traveled to Samoa last month. The team, funded by a National Science Foundation (NSF) grant, collected data Oct. 4 through Oct. 11 to document the impacts of the 8.
Twenty medical students from the University of Central Florida College of Medicine will cook and serve meals to families of ill children Saturday, Nov. 7, at the Ronald McDonald House on the campus of Arnold Palmer Medical Center. It will be the first official community service event for the 41-member charter class, which began classes in August.
The SAVI™ 6-1Mini breast brachytherapy applicator is the only brachytherapy solution for patients with small breasts, hard-to-reach lumpectomy cavities, or cavities close to the skin surface, according to a new study.
ERYtech Pharma announces the start of its pivotal clinical trial for GRASPA®, its lead product in Acute Lymphoblastic Leukaemia. This phase III trial has begun in France and will be enlarged to a European scale. Up to 80 patients with relapsed Acute Lymphoblastic Leukaemia, aged from 1 to 55 years old will be enrolled.
Results of the FDA pivotal clinical trial for the LightTouch™ Non-invasive Cervical Cancer Detection Device conducted by Guided Therapeutics, Inc. (GT) (Pink Sheets: GTHP), indicated that the current system for diagnosing cervical disease missed the same amount of disease as a landmark study carried out by the National Cancer Institute (NCI).
As the debate heats up concerning the use of electronic cigarettes, Electronic Cigarette Association (ECA) President Matt Salmon today encouraged those involved in this discussion to carefully and honestly study how these devices work and recognize that the more than one million adult committed smoke